[4] He was selected by the San Diego Padres in the second round (39th overall) of the 2017 Major League Baseball draft and he signed for $1.3 million, forgoing his commitment to South Carolina.
[7] He spent 2018 with the Fort Wayne TinCaps where he slashed .288/.345/.365 with three home runs and forty RBIs in seventy games and was named a Midwest League All-Star.
[8][9] Campusano spent 2019 with the Lake Elsinore Storm, earning California League All-Star honors.
[16] To begin the 2021 season, Campusano was assigned to the major league roster before being optioned to the El Paso Chihuahuas of the Triple-A West in late April.
[22] Campusano's father, Genaro, signed with the Pittsburgh Pirates as an international free agent in 1989 and spent four years playing in their minor league system.
[23] On October 17, 2020, Campusano was arrested in Grovetown, Georgia and charged with a felony after he was pulled over by police and found to be in possession of 79 grams of marijuana.