Luis Ernesto Derbez Bautista (born April 1, 1947, in Mexico City) is a Mexican politician and rector of the Universidad de las Américas Puebla (UDLAP).

[6] Before joining the Fox campaign in 1997, he worked 14 years for the World Bank, managing economic adjustment programs in Africa, Asia and Central America.

At the 2001 WTO's Ministerial Meetings in Qatar he was a member of the Director's Team which successfully negotiated the start of the Doha Development Round.

By 2005, over $10 billion in new investments were attracted by those programs in the automotive, electronics, and maquiladora industries, allowing the nation to regain some of its presence in world markets despite the failure to reach structural economic reforms sought by the Fox government.

In January 2003, following the resignation of Jorge Castañeda, Derbez took over as Secretary of Foreign Affairs, a position that he held until President Vicente Fox's term ended on December 1, 2006.

Its work has led to a program entitled Security and Prosperity Agreement (ASPAN for its acronym in Spanish), launched in 2003 in Waco, Texas, by the three leaders of the North American countries.

One of the major results of ASPAN was the constitution of a private-public Competitiveness Council which is defining sector specific policies to standardize the region's economic environment.

Under Derbez's leadership, Mexico gained associated status in the Andean Countries Group and MERCOSUR, while at the same time signed a strategic, political, and economic alliance with Chile.

Since January 2007, Luis Ernesto Derbez has been the General Director of the Centre for Globalization, Competitiveness and Democracy at the Instituto Tecnológico de Monterrey, Campus Santa Fe, and Secretary for International Affairs of the PAN.