Louie Main Medina (born March 26, 1963) is a former designated hitter/first baseman in Major League Baseball who played for the Cleveland Indians (1988–89, 1991).

[1] Drafted out of Arizona State University, the 6 ft 3 in (1.91 m), 220-pound Medina reached the major leagues for good in 1988 after leading all Triple-A players with 28 home runs for Colorado Springs.

He also finished fourth in the Pacific Coast League with 81 RBI and hit .310, despite being disabled three weeks with an elbow injury.

[1] Medina hit .255 with six home runs and eight RBI in 51 at-bats following his late season promotion, but new injuries affected his playing time in the next two years.

[2] Medina was one of those rare players who were not primarily pitchers in major league history who threw left-handed but batted right-handed.