Luisa Contessina Romola di Lorenzo de' Medici, known as Luigia, (1477 – 1488) was an Italian noble.

[1] She was the eightborn and fourth daughter of Lorenzo de' Medici and Clarice Orsini.

[2] She was going to marry with her fiancé Giovanni di Pierfrancesco de' Medici, but she died in 1488 at the age of 11.