Lusby's Mill is an unincorporated community in northern Owen County, Kentucky, United States.

There was a post office that operated in Lusby's Mill from 1852 to 1904 and the town was incorporated in 1869.

There was a distillery that was said to produce “fine quality of pure old copper distilled whiskey” which closed in 1897.

After a bypass road was constructed, business activity diminished in the settlement, and it is no longer incorporated.

This Owen County, Kentucky state location article is a stub.