In the northeast of the district, the Mshinskoye Boloto Zakaznik was created to protect the swamp landscape with the pine-tree forest.

In 1617, according to the Treaty of Stolbovo, the north of the area was transferred to Sweden, the border was drawn at the Oredezh and Luga Rivers.

In 1782, it became the administrative center of Luzhsky Uyezd of Saint Petersburg Governorate (renamed Petrogradsky in 1913 and Leningradsky in 1924).

In 1918, important events of the Russian Civil War took place in the area, when the White Army unsuccessfully tried to conquer Petrograd.

[9] On August 1, 1927, the uyezds were abolished and Luzhsky District, with the administrative center in the town of Luga, was established.

[13] After the abortive administrative reform of the 1960s, its territory became split between Slantsevsky, Volosovsky, Luzhsky, and Kingiseppsky Districts.

In mid-September 2017, during exercise Zapad (West) 2017 and fire-power demonstration for media and other civilians, a Ka-52 helicopter fired a missile that hit the ground near spectators in a parking area.

The main agricultural specializations within the district are cattle breeding with milk and meat production, and potato growing.

The one lying to the east connects Saint Petersburg with Novosokolniki via Dno, with the principal station being Oredezh.

Another one, lying to the west, connects the Baltiysky railway station of Saint Petersburg and Pskov, passing through Luga.

The M20 highway, connecting Saint Petersburg with Pskov and eventually with Kyiv crosses the district from northeast to southwest, passing Luga.

In Luga, two more roads branch eastwards: One running to Veliky Novgorod, and another one to Lyuban and Mga, largely following the border of Leningrad Oblast.

[17] The federal monuments are the wooden Chapel of Saints Peter and Paul in the village of Zakhonye, the tomb of Dmitry Lyalin, and officer who participated in the Patriotic War of 1812, in his former estate in the village of Zaplotye, and a monument to fallen Soviet partisans.