Born in Connecticut and raised in Brookline, Massachusetts, both of her parents were illustrators.
"[8] Biba closed after 9/11 and reopened as Excelsior Restaurant and Shire was hired as Executive Chef.
[6] When Shire bought Locke-Ober with business partner Paul Licari in 2001, she became the historic restaurant's first female chef.
[11] Shire is married to former employee Uriel Pineda, and currently lives in Stoneham, Massachusetts.
After cooking in restaurants in Spain, California and other locales, Alex Pineda worked as a chef with his mother at Scampo in Boston and in spring 2021, became the executive chef at The Landing, a seafood restaurant in Marblehead, Massachusetts.