The airport is named in honor of the jurist and politician Manuel Crescencio García Rejón, who was originally from Yucatán.

[3] The airport's history traces back to its inauguration in 1929 when Mexicana de Aviación introduced the Mérida-Campeche-Ciudad del Carmen-Minatitlán-Veracruz-Mexico City route, operated with a Ford Trimotor aircraft.

During the 1990s, the airport became part of the Grupo Aeroportuario del Sureste, marking an important instance of a private concession within this group.

This consortium encompasses various airports, including Cancún, Cozumel, Huatulco, Mérida, Minatitlán, Oaxaca, Tapachula, Villahermosa, and Veracruz.

[4] The airport is situated in the Mérida urban area, less than 5 kilometres (3.1 mi) southwest of the city centre, at an elevation of 12 metres (39 ft) above sea level.

The ground floor comprises the main entrance, a check-in area, and the arrivals section, which includes customs and immigration facilities, along with baggage claim services.

Within this section, there are restaurants, food stands, duty-free shops, VIP lounges, and eleven gates (C1-11), with seven of them equipped with jet bridges.

[8] Operated by the Mexican Airspace Navigation Services (Spanish: Servicios a la Navegación en el Espacio Aéreo Mexicano), Mérida ACC provides air traffic control services for aircraft operating within the Mérida Flight Data Region (FDRG), which encompasses the southeastern region of Mexico.