Mỹ Xuyên is a rural district (huyện) of Sóc Trăng province in the Mekong Delta region of Vietnam.

As of 2003 the district had a population of 197,876.

[1] The district covers an area of 544 km2.

The district capital lies at Mỹ Xuyên.

This article about a location in Sóc Trăng Province, Vietnam is a stub.