During the 1960s and 1970s, M-14 was moved to the freeway alignment it currently uses; sections of the former route are still maintained by the Michigan Department of Transportation (MDOT) as unsigned highways.

US 23/M-14 then has an unusual right-in/right-out interchange that uses short connector roads to provide access to Barton Drive on the north side of the river.

The business loop ends there, and M-14 turns eastward to follow the US 23 freeway around the north side of Ann Arbor.

[4][5] The US 23/M-14 freeway runs for about one mile (1.6 km) before US 23 turns southward to run between Ann Arbor and Ypsilanti while M-14 continues east through Ann Arbor Township past Domino's Farms,[4][5] the office complex for Domino's Pizza that was to be the home to Tom Monaghan's Leaning Tower of Pizza.

There is a crossing for another CSX rail line near the bridges over the River Rouge by the St. Johns Golf Course.

As M-14 nears the Livonia city line, it meets an interchange with I-96 and I-275 that marks the eastern terminus of M-14 in Plymouth Township.

[8] All of M-14 has been listed on the National Highway System,[9] a network of roads important to the country's economy, defense, and mobility.

[2][3] In 1964, a northern bypass connecting US 23 with M-153 was completed, and M-14 was rerouted onto the new freeway; the highway still ran through Ann Arbor along routes now designated Bus.

[20][21] The following year, the freeway was extended to its present western terminus at I-94, and M-14 is removed from the business routes and transferred to the expressway.

[23][24] The portion of Plymouth Road–Ann Arbor Road between I-275 and the city boundary with Redford Township was retained as an unsigned trunkline, maintained by the state to this day.

[26][27] The portion of Ann Arbor Road from the Wayne County line east to I-275 also became an unsigned state trunkline, also still maintained by MDOT.