The M27 road is a short metropolitan route in the City of Tshwane in Gauteng, South Africa.

It begins by heading eastwards as Theuns van Niekerk Street for a few metres before becoming Estcourt Avenue eastwards and reaching a junction with the R101 route (Old Johannesburg Road) in Hennopspark.

The M27 continues eastwards as Lenchen Avenue to fly over the N14 highway (Ben Schoeman Freeway) and pass through the Zwartkop suburb to enter the Centurion CBD, where it temporarily becomes two one-way streets and meets the M19 route (John Vorster Drive).

It heads east-north-east, bypassing Centurion Mall before crossing the Hennops River on the south-eastern side of Centurion Lake (where it ceases to be one-way streets) and entering Die Hoewes, where it meets the M34 route (Jean Avenue).

Just after meeting the M18, the M27 turns to the south-east as Theron Street for 1.7 kilometres before bending towards the north-east (bypassing the southern boundary of the Waterkloof Air Force Base) and heading another 2 kilometres to reach its end at a junction with the M28 route (Van Ryneveld Avenue) just north of Pierre van Ryneveld Park.