The M5 motorway (Hungarian: M5-ös autópálya) is a Hungarian motorway which connects Budapest with the south-eastern regions of the country, the cities of Kecskemét, Szeged, and finally Röszke on the Serbian border.

The motorway reached the city of Szeged in December 2005, while the remaining portion (between Szeged and Röszke) was completed in April 2006.

The M5 continues as the A1 motorway in Serbia from the Serbian side of the border at Horgoš.

It is also the main route from Budapest to Bucharest via the M43 motorway and Romania's A1 motorway, as the link has been opened to traffic since July 2015.

Parts of the road are under operation & maintenance by a private concessionaire AKA Zrt.