378938n/aENSG00000251562n/anan/an/an/an/an/aMALAT1 (Metastasis Associated Lung Adenocarcinoma Transcript 1) also known as NEAT2 (Nuclear-Enriched Abundant Transcript 2) is an infrequently spliced long non-coding RNA, which is highly conserved amongst mammals and highly expressed in the nucleus.

[5] MALAT1 may play a role in temperature-dependent sex determination in the Red-eared slider turtle (Trachemys scripta).

[6] Transcripts of MALAT1 are significantly increased in the cerebellum of human alcoholics, as well as in similar regions of rat brains after the withdrawal of ethanol vapours.

This alcohol-induced upregulation of MALAT1 may be responsible for differential expression of a number of proteins which contribute to ethanol tolerance and dependency in humans.

[7] Elevated MALAT1 expression is correlated with poor overall survival in various types of cancer, suggesting that this gene is a prognostic factor for different types of cancer.