[5] It is also known as HPK1 (Hematopoietic Progenitor Kinase 1).

The protein has been shown to play a role in JNK activation.

[6] MAP4K1 has been shown to interact with: Optimization of inhibitors of MAP4K1 for upregulating the T cell receptor signaling pathway has produced at least one compound that exhibits antitumor activity in an EMT6 syngeneic mouse model, and is an area of ongoing research.

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