MSD and VCR are administered intravenously, while procarbazine and prednisone are pills taken orally.
MOPP was the first combination chemotherapy brought in that achieved a high success rate.
It was developed at the National Cancer Institute in the 1960s by a team that included Vincent DeVita, Jr.
Although no longer the most effective combination, MOPP is still used after relapse or where the patient has certain allergies or lung or heart problems which prevents the use of another regimen.
Nausea, vomiting, and stomach ache are common, as are chills, constipation, and frequent urination.