The four-cylinder engine had its capacity expanded to 750cc by increasing the bore, the exhaust system was upgraded and the seat, tank and handlebars were changed to more sporting items.

The rack took the nine-piece crankshaft in six bearing blocks, as well as the spur gears in the control tower for the double camshaft drive.

[9] Particularly striking was the fine ribbing of the cooling fins of the sump as well as the oversized cylinder head caused by the double camshaft drive.

Two model variants were available based on the MV Agusta 750 S:[12] Two machines were modified to Formula 750 racing specification for Giacomo Agostini and Nello Pagani to ride in the 1972 Imola 200.

Many of the cycle parts from the 500 racers were used: Ceriani forks and brakes, Borrani rims etc., bringing the weight of the machine down to 190 kg.