Maathorneferure (Hieroglyphic: Mȝʿt-Ḥr-nfrw-Rʿ, Maʿat-ḥōr-nefrurēʿ)[1] was an ancient Egyptian queen, the Great Royal Wife of Ramesses II (1279–1213 BC, according to the standard "Low Chronology" for Egypt).

[13] The status of Maathornefrure as the King's Great Wife (unlike Ramesses' other foreign wives), seems to have been a precondition of the marriage alliance, set by her parents.

Alternatively, it is possible that "maʿat-ḥōr" was a queenly title or epithet ("One who sees Horus"), and the new Egyptian name of the princess was more simply Nefrurēʿ ("the Splendor of Ra").

Ramesses II expressed concern over continuing delays, while the Hittite queen Puduhepa explained that she had to send off her daughter in style with a suitable dowry, which was difficult to assemble quickly.

[23] Later, Ramesses II sent a military escort to ensure the safety and honor of his bride, and she marched on to Egypt under the protection of both Hittite and Egyptian troops.

[25] Maathornefrure was traveling with a vast escort, including troops guarding the princess and her dowry caravan laden with gold, silver, bronze, cattle and sheep, and slaves.

[26][4] At the Egyptian frontier, a message was dispatched to the Pharaoh: "They have traversed sheer mountains and treacherous passes to reach Your Majesty's border.

Nevertheless, Maathornefrure resided at court for at least a while, receiving emissaries from her father,[33] before apparently settling in the harem palace at Mer-wer (today's Gurob).

[46] While the situation was markedly different from that described in the "Bentresh stela," the Hittite king Hattusili III did seek Ramesses II's assistance in curing his aging sister Matanazzi/Massanauzzi's infertility.

In a surviving letter, Ramesses informed Hattusili that his sister was past childbearing years, but nonetheless promised to send a priest and physician to try to help her.