[1]: 35  Constructed in 1934 during centenary celebrations of Victoria, MacRobertson was vital to the progress of modernist architecture in Australia and essential in the strong re-emergence of the state after the economic downturn of the depression.

[1]: 44 It is believed that the main influence of Seabrook's design for MacRobertson Girls’ High School was William Dudok Hilversum’s town hall (1923–31).<[1]: 39  Both these buildings have similar brickwork, rectilinear interlocking facades, functional planning, open air classrooms, flat roof, industrial aesthetic and a modern interior fitout.

[1]: 40  This frame of mind helped in creating the unique and functional design of the building which has had a great impact on Australian architecture.

[5] The differing masses of MacRobertson impart proportion and scale to the building,[6]: 10  while the De Stijl colour of the articulated red steel hopper windows contrast to the blue glazed brick piers and cream brickwork, helping to break up the facade.

Seabrook also considered the site in his design, using native plants to embrace the dry, flat scrubland of South Melbourne.