Macamic (French pronunciation: [makamik]) is a ville in northwestern Quebec, Canada, in the Abitibi-Ouest Regional County Municipality.

Colonization began at the time when the National Transcontinental Railway running through the Abitibi region was completed.

The first pioneers, arriving circa 1913, were originally from Saint-Ignace-du-Lac, Pierreville, Stanfold, Nicolet, and Shawinigan.

In 1924, Poularies Township also separated from Royal-Roussillon-et-Poularies, which became the Parish Municipality of Royal-Roussillon-de-Macamic in 1952, and officially shortened to just Macamic in 1961.

In the 2021 Canadian federal election, the incumbent Sébastien Lemire of the Bloc Québécois was re-elected to represent the population Macamic in the House of Commons of Canada.