Macromerine is a phenethylamine derivative.

It was first identified from the cactus Coryphantha macromeris.

[1] It can also be found in C. runyonii,[2] C. elephantidens, and other related members of the family Cactaceae.

Macromerine is a phenethylamine derivative with the molecular formula C12H19NO3.

At least one study found macromerine to be non-psychoactive.