Macrothelypteris is a genus of ferns in the family Thelypteridaceae, subfamily Phegopteridoideae, in the Pteridophyte Phylogeny Group classification of 2016 (PPG I).

[2] The genus name means 'large Thelypteris'.

[3] As of January 2020[update], the Checklist of Ferns and Lycophytes of the World and Plants of the World Online (POWO) listed the following species and one hybrid:[1][4]

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