Madame Hydra

[4] After keeping the Taskmaster and the Black Ant alive and persuading them to become her personal guards, Elisa then collects a new HYDRA High Council consisting of herself, a new Kraken, the Gorgon, the Hive, the Viper, Baron Helmut Zemo, Arnim Zola, and Doctor Faustus.

[5] During the "Opening Salvo" part of the Secret Empire storyline, Elisa reunites with Captain America after he overthrew the Red Skull for leadership of HYDRA.

[6] While in her study room following HYDRA's takeover of the United States, Elisa uses her magic spells to counter every one of Doctor Strange's attempts to bring down the Darkforce dome that is surrounding Manhattan.

Elisa brushes off the suspicion and tells Captain America that they plan to assemble the Cosmic Cube in order to restore Earth to their vision.

[11] Valentina Allegra de Fontaine and Viper appear in Nick Fury: Agent of S.H.I.E.L.D., portrayed by Lisa Rinna and Sandra Hess respectively.

Mallory Jansen as Madame Hydra, as depicted in Agents of S.H.I.E.L.D.