Madison West's advanced placement classes include French Language and Culture, Spanish Language and Culture, Spanish Literature and Culture, German Language and Culture, U.S. Government & Politics, U.S. History, World History, Statistics, Precalculus, Calculus AB, Calculus BC, Computer Science Principles, Computer Science A, Physics 2, Chemistry, Biology, Environmental Science, and Music Theory.

Notable examples include: Forensics, Debate Club, Science Olympiad, Mock Trial, and DECA.

[6][7][8] In 2020, the club submitted a proposal to the Ken Sousa Memorial Grant Contest to study the effects of space flight on organisms by sending slime molds into suborbital flight.

[9] The club completed Project Ariadne, putting slime mold through the stress of going on a suborbital flight and studying its ability to solve mazes and develop pathways competing in the 2020 NASA Student Launch Challenge.

working on the American Rocketry Challenge and Rockets For Schools, where they have regularly placed at finals.