Madisonville North Hopkins has a curriculum of several Advanced Placement classes, including: English Language and Composition, English Literature and Composition, World History: Modern, United States History, Government and Politics: United States, Spanish Language and Culture, Spanish Literature and Culture, Calculus AB, Statistics, Biology, and Chemistry.

The Madisonville North Hopkins Maroon "powerlifting" team has won the AAA state championship for 4 years, however, it is not a KHSAA sponsored sport.

The Future Problem Solving team won the international championship in 2006 and 2007.

The Madisonville North Hopkins Maroon cheerleaders were the 2009 KAPOS Small Varsity State Champions.

In the present context, the school no longer encompasses a competitive bass fishing team, yet it is noteworthy that there exists a collective desire among the students for the school to feature a fishing team.