Mae Charim Wildlife Sanctuary (Thai: เขตรักษาพันธุ์สัตว์ป่าแม่จริม; RTGS: Khet Raksa Phan Satpa Mae Charim) is a wildlife sanctuary in Ban Khok, Fak Tha and Nam Pat districts of Thailand's Uttaradit Province.

The sanctuary covers an area of 660 square kilometres (250 sq mi) and was established in 1998.

Mae Charim Wildlife Sanctuary is located about 85 km (53 mi) northeast of Uttaradit town in Bo Bia, Muang Chet Ton subdistricts, Ban Khok District and Fak Tha, Song Khon, Ban Siao, Song Hong subdistricts, Fak Tha District and Den Lek, Tha Faek subdistricts, Nam Pat District of Uttaradit Province.

[3] The sanctuary's area is 660 square kilometres (250 sq mi) and is neighbouring Nam Pat Wildlife Sanctuary to the southeast and Lam Nam Nan National Park to the southwest and abutting Si Nan National Park to the west.

[4] The small streams are tributaries of the Nan River and Nam Pat.