[1] D'Agostino received a Bachelor of Arts, magna cum laude, from Siena College in 1977 and a Juris Doctor from Syracuse University College of Law in 1980.

[2] D'Agostino practiced law in the Albany area, and was a partner in the firm of D'Agostino, Krackeler & Maguire, which focused on representing doctors, hospitals, and insurance companies in medical malpractice cases.

[3] On June 23, 2010, Senator Chuck Schumer recommended D'Agostino to fill a vacancy on the United States District Court for the Northern District of New York.

[4] On September 29, 2010, President Barack Obama formally nominated her to the Northern District of New York.

[5] On March 28, 2011, the United States Senate confirmed her nomination by a 88–0 vote.