[2][Note 2][3] The synagogue was destroyed in 1988 by the orders of then President of Pakistan, Muhammad Zia-ul-Haq,[4][3] following which a shopping plaza was built in its place.

In 1916, the Jewish community of Karachi, India, opened a Hebrew school on the synagogue premises, and later constructed the Nathan Abraham Hall in 1918.

[2] The synagogue soon became the centre of a small but vibrant Jewish community, one of whose leaders, Abraham Reuben, became a councillor on the Karachi city corporation in 1936.

[7] On 17 July 1988, the synagogue was demolished[7] and eventually replaced by a shopping plaza (Madiha Square) in the Ranchore Line neighbourhood of southern Karachi.

In 1989, the original ark and podium were reportedly stored by a non-Jew in Karachi, while a Torah scroll case was taken by a Jewish American woman to the United States.