Magandang Buhay premiered on ABS-CBN on April 18, 2016 every Monday to Friday at 07:30 (PST), replacing Kris TV.

[1] The title of the show is inspired by a popular line from the Philippine television drama series Dream Dad.

[3] On March 10, 2020, the admission of live audience members to the show was suspended following a public health emergency in response to the COVID-19 pandemic.

[5] On May 5, 2020, Magandang Buhay was suspended after ABS-CBN permanently ceased the free-to-air broadcast operations as ordered by the National Telecommunications Commission (under the leadership of Gamaliel Cordoba) and Solicitor General Jose Calida.

[7] In 2022, Karla Estrada was on temporary leave due to her commitment with Tingog Party List in the Philippine House of Representatives elections.