Maguari orthobunyavirus, abbreviated MAGV,[1] is a negative-sense, single-stranded RNA virus in the Bunyavirales order, genus Orthobunyavirus,[2][3] Bunyamwera serogroup,[3] that has been shown to be capable of causing human disease.

[1] In addition to humans, MAGV has been isolated from mosquitoes, horses, cattle, sheep, birds, and rodents.

[1] The mosquito species include Aedes fulvus, Aedes scapularis, Aedes serratus, Culex taeniopus, and species in the genera Anopheles, Wyeomyia, and Psorophora.

[1] MAGV's geographic range includes Argentina, Brazil, Colombia, French Guiana, Guyana, and Peru.

[4] The presence of antibodies to Maguari virus in human residents of south Florida can be attributed to either cross-reactivity with Tensaw virus, or cross-reactivity to an antigenic subtype or variant of Tensaw virus, although it is possible that another, undescribed, Bunyamwera serogroup virus may exist in south Florida.