The highway runs 15.9 miles (25.6 km) along the western banks of the Sandy River entirely in Franklin County.

After passing through the settlement of South Strong, SR 149 continues traveling through forested areas before climbing a small hill to intersect SR 234 (Norton Hill Road).

After curving to the northwest, it enters Phillips and passes a line of small houses.

It makes a 90-degree bend to the south to cross the Sandy River on a narrow bridge.

It makes another 90-degree bend to the west to travel along Main Street through Phillips's business district.