The Maison de la Culture de Grenoble, commonly called MC2, is a public venue for public events located on the Avenue Marcellin-Berthelot in Grenoble, France.

Built by André Wogenscky on the occasion of the 1968 Winter Olympics, MC2 was inaugurated on 3 February 1968 by André Malraux, Minister of Cultural Affairs and the father of the concept of houses of culture.

The Maison de la Culture has been called MC2 since 17 September 2004 when it reopened after extensive rehabilitation and expansion at a cost of €38 million, covered 42.3% by the city, 40% by the state, 10.7% by the department and 8% by the Region.

The main hall, which is lined with wood panelling, was built during the renovation work to replace a rotating theatre.

The MC2 is a "public institution of cultural co-operation" (établissement public de coopération culturelle) funded by the Ministry of Culture, the City of Grenoble and the Isère General Council.