Maharashtra Major State Highway 1, commonly referred to as MH MSH 1, is a major state highway that runs south through Dhule and Nandurbar districts in the state of Maharashtra.

This state highway touches numerous cities and villages, namely Songir, Chimthane, Dondaicha, Nimgul, Shahada, Dhadgaon, Kathi, Molgi, Wadifali and then proceeds south-west towards Maharashtra-Gujarat state border.

This highway enters Gujarat State near Wadifali village which is on border of Nandurbar district of Maharashtra and Narmada district of Gujarat and ends at Dumkhal village which is just 15 km South-East of Sardar Sarovar Dam.

This highway starts off from intersection of National Highway 3 near Songir village and proceeds North-West towards Sondale village in Sindkheda Taluka.

Many villages, cities and towns in various districts are connected by this state highway.