The Malesanden and Huse Wildlife Sanctuary (Norwegian: Malesanden og Huse dyrefredningsområde) is located on the east side of Harøya island in the municipality of Ålesund in Møre og Romsdal county, Norway.

The area consists of a low, wide sandy beach that is a nesting, resting, and overwintering site for various birds: waders, the common shelduck, and the greylag goose.

Waterfowl and seabirds overwinter to such an extent that it is considered to have national or even international importance.

The Malesanden and Huse Wildlife Sanctuary is a 15.2-square-kilometer (5.9 sq mi) buffer zone with two subareas covering 71.8 hectares (177 acres): the Malesanden Bird Sanctuary (Norwegian: Malesanden fuglefredingsområde) and the Huse Bird Sanctuary (Norwegian: Huse fuglefredingsområde).

The wildlife sanctuary is one of six natural areas that were included in the Harøya Wetlands System Ramsar site, which was established in 1996.