It was started in 1755 when the Governor General of the Philippines ordered the expulsion of the Chinese from the Philippines due to their participation in some rebellion and sedition acts against the Spanish Government.

On documents such as the Registros Paroquiales or The Catholic Baptismal Registry of Malolos, the town already had its own "Parian" (a kind of Chinatown) in 1710.

A provision in the segregation order also stated that only those Chinese who have long been residents of the town who have married a native of Malolos will not be expelled.

Thus the Sangleys of Malolos were born and the Pariancillo became the Chinese enclave in Bulacan Province.

The National Historical Institute board resolution cites several reasons for the declaration of certain areas in downtown Malolos as a National Historical Landmark and Heritage Town, or informally as parts of a Historic Town Center:[1] According to the board resolution, the following streets are identified as part of the Malolos Historic Town Center:[1] The following table lists down extant built heritage within the areas declared by the National Historical Institute: The following table lists of structures in Malolos extant built heritage outside the declared National Historical Landmark by the National Historical Institute but are still covered by the National Cultural Heritage Act of 2009 as cultural property:[4] One of the features of Malolos Historic Town Center are the monuments created by the artisans and National Artist can be found at different areas in the city.