[2] Recently, a better approach to annotate active promoters has been demonstrated with a combination of ChIP-seq and computational technique.

[3] This technique has been used to find the target genes of TFs in mammalian systems.

The MPromDb data base added active RNAP-II promoters identified after analyzing ten different mouse cell/tissue ChIP-seq experiments performed with RNAP-II antibodies and six different human cell types.

[1] The data was acquired by a series of computational methods followed by manual correction to ensure its high level quality.

[2] In the newest version of MPromDb, about 507 million uniquely-aligned RNA Pol-II ChIP-seq reads have already been analyzed from 26 different databases, including six human cell-types and 10 distinct mouse cell/tissues.