Manchester is a town in Grant County, Oklahoma, United States.

[4] Manchester is located in northwest Grant County just south of the Oklahoma-Kansas border along SH-132.

The Atchison, Topeka and Santa Fe Railroad passes through the town.

[5] According to the United States Census Bureau, the town has a total area of 0.2 square miles (0.52 km2), all land.

34.0% of all households were made up of individuals, and 17.0% had someone living alone who was 65 years of age or older.