Currently it plays in Serie D. The club, founded in 1932 as Associazione Sportiva Manfredonia.

[citation needed] Manfredonia is known for having been the first Italian professional team to play its home matches on a synthetic football field.

The club also won the appeal to remain in the professional league in July 2008.

[4] At the end of the 2009–10 Lega Pro Seconda Divisione season, the company had major financial problems that led the team to failure.

[9] In July 2016 the football club was incorporated again as a società a responsabilità limitata (means limited liability company): Manfredonia Calcio S.r.l.