Located entirely in the Municipality of Two Borders, it serves as the primary road access to the community of Elva, as well as a connection to Broomhill for PTH 3 (Boundary Commission Trail).

PR 252 begins at an intersection with PTH 3 (Boundary Commission Trail) roughly halfway between Pierson and Melita.

It heads due north to cross a railway line and travel through the western side of the community of Elva.

The highway continues north through rural farmland for several kilometres to cross PR 445 before coming to an end at a junction with PR 345, 2.0 kilometres (1.2 mi) west of Broomhill.

[1][2] Prior to 1992, PR 252 continued north for an additional 61.8 kilometres (38.4 mi), following short concurrencies with PR 345 west of Broomhill and PTH 2 (Red Coat Trail) in Reston, it crossed Pipestone Creek before traveling through Woodnorth to have intersections with PR 255 and PR 257 before coming to an end at an intersection with PTH 1 (Trans-Canada Highway) at Hargrave.