Emmanuel "Manny" Santo Domingo Lopez (born June 30, 1958)[2] is a Filipino political activist who advocates direct democracy.

In UP, Manny SD Lopez started as a regular student scaling up to scholarly standard as he joined and became active officer of the prestigious Upsilon Sigma Phi.

In a July 2015 forum in Cebu City, Lopez said the BBL is a clear and present danger to the Philippines' national security, interest and welfare, stating that it was patterned after the Federation of Malaysia.

"The Malaysian interest in the passage of the BBL is not to help Filipino Muslims; (the law) is designed for the purpose of creating a buffer state that prevents the Philippines from enforcing its legitimate claim on Sabah," Lopez said.

[9][10] In 2014, however, Lopez called the Archbishop of Cebu to seek the agglomeration of all groups on the same people's-initiative route that EPIRMA was taking in order to form a united front or coalition.

[11][12][13][14][15] Meanwhile, at the same time that EPIRMA prepared for its participation in the initiative launch, Lopez had also been criticizing purportedly questionable military purchases under the Aquino administration.