Manuel Pérez de Guzmán y Pimentel, 12th Duke of Medina Sidonia (1671–1721) became Duke of Medina Sidonia in 1713.
He was married in 1687, aged 16, to the 17-year-old Luisa Maria de Silva Mendoza.
She was a daughter of Gregorio Maria Domingo, the 5th Duke of Pastrana, 5th Duke of Estremera and 9th Duke of el Infantado.
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