Mapperley Hospital was a mental health facility on Porchester Road in Nottingham, England.

The hospital, which was designed by George Thomas Hine using a linear corridor layout, opened as the Nottingham Borough Lunatic Asylum in August 1880.

[1] After the introduction of Care in the Community in the early 1980s, the hospital went into a period of decline and closed in December 1994.

The north end of the campus has been renamed "Duncan Macmillan House" and is now used as the headquarters of the Nottinghamshire Healthcare NHS Foundation Trust[3] while the south end of the campus has been renamed "Nightingale House" and has been converted into privately owned apartments.

[4] Meanwhile, a modern mental health facility, known as the Wells Road Centre, has been established to the west of the site and provides low secure in-patient services.