Sabrisho I (also Sabr-Ishu, Syriac for "hope in Jesus") was Patriarch of the Church of the East from 596 to 604, during the rule of King Khosrow II.
He was involved in the conversion of King Nuʿman III of Ḥirta of the Lakhmid kingdom.
[1] Shortly after his appointment in 596, he started to convene a synod which was held in 598 in Seleucia-Ctesiphon[2] where he anathematized the opponents of Theodore of Mopsuestia.
[3] Other conflicts during Sabrisho's tenure included that with Henana of Adiabene, who he excommunicated from the Church.
There was a subsequent power struggle over the election of a new Patriarch, between the King, his wife Shirin, and the Synod (council) of bishops.