Marble Hill is a fourth-class city in central Bollinger County in Southeast Missouri, United States.

Located at the intersection of State Highways 34 and 51, it is the largest city in Bollinger and serves as the county seat.

Marble Hill is part of the Cape Girardeau−Jackson, MO-IL Metropolitan Statistical Area.

As the area grew over the years, the First Baptist Church was built in 1856 near the oldest cemetery in Marble Hill.

Finally, in 1868, the name of the town was changed again, this time to Marble Hill, to prevent confusion with the already existing Dallas County.

Lutes offered 10 acres (40,000 m2) to the railroad for a depot location which would be used as a shipping and trading point.

Disputes with leaders of Marble Hill persuaded the railroad to relocate their route through Lutesville instead.

In 1893, Wicecarver's Store was built across from the courthouse where the steps in front were formerly used for mounting horses and carriages.

The year 1932 marked the last passenger line on the Belmont Branch of the St. Louis & Iron Mountain Railroad.

In August 1953, an artesian well was discovered approximately 1,800 feet (550 m) deep while drilling for oil in the area.

Lutesville, which had been founded in 1869 and later became the main business and shipping center for the area, merged with Marble Hill and maintained the name of Marble Hill because it was the current county seat.

The Woodland R-IV School District serves the educational needs of most of the city's residents and nearby throughout central Bollinger County.

Precipitation is abundant with an annual average of 48.58 in (1,234 mm); the spring and autumn months typically are the wettest parts of the year.

Among the major first ancestries reported in Marble Hill are 16.2% German, 14.5% English, 14.4% Irish, 11.4% American, 5.4% Dutch, and 3.4% French.