In 1999, he began doctoral studies researching chromosome breakage syndrome, fanconi anemia, gene mutations, and acute myeloid leukemia.

[1][3] His 2003 dissertation was titled The role of mutations in Fanconi Anaemia genes in the aetiology of acute myeloid leukaemia and solid tissue malignancies.

He is the former Chair of the UK Cancer Genetics Group and was an executive member of the GENTURIS European Reference Network for rare hereditary tumour syndromes.

[citation needed] Tischkowitz's research focuses on Fanconi Anemia genes and hereditary breast cancer predisposition such as PALB2.

Other areas of research include hereditary diffuse gastric cancer, small cell carcinoma of the ovary and Ataxia Telangiectasia.