Marcello Spatafora (born 30 July 1941) is a retired Italian diplomat, former Permanent Representative of Italy to the United Nations.
From 2000 until April 2003, he served in the Italian Ministry of Foreign Affairs as Director General for Multilateral Economic and Financial Cooperation.
In 1989-1990 he was the Chief of the Italian Delegation responsible for organizing the country's presidency of the European Economic Community.
Since 2008, he has been a staunch supporter of United Nations activities worldwide, including, in particular, the humanitarian relief efforts led by OCHA.
Order of Merit of the Italian Republic 1st Class / Knight Grand Cross – June 2, 2005