She took a position as a relief worker on a salary of $15 a month at the Enoch Pratt Free Library, led by Dr. Bernard Steiner, where she continued to work for three years.

Because of her work at the Enoch Pratt Free Library, Steiner recommended Noyes for the position, declaring her "a woman of executive talents".

Due to budgetary constraints, Noyes was only able to hire one full-time assistant, Gustave Orville Caution, during the first ten years of her employment .

"[3] One of the earliest mandates of the MLA was the Exchange, a distribution and trade service for those who had duplicates or little-used books in their collections.

In 1904, the Exchange was again moved to the Medical Society of the County of Kings (Brooklyn, New York) due to storage constraints, and in 1908 the MLA asked Noyes to take charge once again.

In 1909, when the new Faculty building opened, providing enough room to run the Exchange and with the help of MLA Treasurer, Dr. John Ruhräh.

[3] Additionally, Noyes and Ruhräh worked jointly to revive the Bulletin of the Medical Library Association, which had all but ceased publication in 1908, taking the Exchange with it.

[2][6][7] Noyes wanted to write the history of the MLA once she retired from full-time work at the Faculty, but her health was beginning to fail.

She was presented with a suitcase, a sum of money to use for traveling, and her favorite painting, which she had persuaded the Library committee to purchase many years earlier.

It is awarded yearly, and presented at the Annual Meeting to a librarian who shows distinguished service and leadership in health sciences librarianship.