Donnarumma is often associated with cyborg[4] and posthuman[5] artists and is acknowledged for his contribution to human-machine interfacing through the unconventional use of muscle sound and biofeedback.

[19] In 2010, feeling increasingly constrained by the conventional ways of interacting with computers on stage, such as digital interfaces and hand-held instruments, Donnarumma began exploring wearable body technologies.

[20] In 2011, for his Master in sound design at the Edinburgh College of Art, he created the XTH Sense as a new instrument for music and body performance.

[23] He later released the schematic and the software of the XTH Sense to the public under open source licenses (GPL and CC similar to the ones used by the Arduino project) sparking widespread interest in the international media and the artistic scene.

[24][25][26] Since then, several artists and researchers have been adopting the XTH Sense as a creative and learning tool in different field of practice, such as dance, music, theatre and engineering.

[39] In Hypo Chrysos (2012), a work inspired by Dante's Inferno,[40] Donnarumma pulls two heavy concrete blocks in a circle for twenty minutes.

[42] In Corpus Nil (2016), the performer's tattooed body slowly mutates from an amorphous shape to an animal-like form by contracting and quivering as if struggling against powerful constraints.

"[43] Donnarumma collaborated with a range of artists across disciplines including performance art, cyberart, spatial sound, and live cinema.

[44] In 2014, he collaborated with computer science researcher Baptiste Caramiaux to create a new work, Septic, commissioned by transmediale festival's Art Hack Day.