[10] Aged 19, Brigstocke worked on a North Sea oil rig,[11] and later as a podium dancer (being featured on Electric Circus); he used his earnings to travel, and the experiences as inspiration for a stand-up routine.

While at Bristol he often performed in the comedy trio Club Seals (with Dan Tetsell and Danny Robins), which later made the transition to television in the series of short programmes We Are History (2000-2001).

[13] In April 2008, Brigstocke and fellow comedian and snowboarder Andrew Maxwell founded a comedy and music festival in the ski resort of Meribel, in the French Alps.

In 2009, Brigstocke starred in the British tour of the American live improvisation show Totally Looped.

In June 2010, he announced that he had signed a publishing deal with Transworld to turn the God Collar Tour into a book,[15] which was released in 2011 to mixed reviews.

Brigstocke has a radio career including The Now Show (1998-2024, with Steve Punt and Hugh Dennis) and Giles Wemmbley-Hogg Goes Off (2002–2011).

[21] In December 2017, BBC Radio 4 broadcast his new 4-part sitcom, The Wilsons Save The World, in which Brigstocke plays a father leading a family trying to live ethically.

In September 2008, Brigstocke was a team captain for the first series of a comedy panel show, Argumental (2008-2012), for the British television channel Dave.

He was the captain of the Red Team, competing against Rufus Hound with a variety of guest participants, under the chairmanship of John Sergeant.

[24] In 2000, he successfully claimed publishing rights after a sample of his voice was used in the song "I Don't Smoke" by DJ Dee Kline.

[25] In 2010, Brigstocke made his musical theatre debut as King Arthur in the British tour of Spamalot for a limited engagement.