Kodansha USA published the manga series in English, and Sentai Filmworks released anime films on DVD and Blu-ray Disc.

However, she is rescued and transformed into a cyborg by Dr. Easter under regulation Mardock Scramble 09, an emergency ordinance where experimental technologies can be used to preserve life.

Rune is trained to use the advanced technology fitted on her to defend herself against Shell's attempts to have her killed to stop her from testifying against him.

The story was written by Tow Ubukata, and illustrated by Katsuya Terada was serialized in Hayakawa's SF Magazine.

[4] A manga adaptation illustrated by Yoshitoki Ōima was published in Kodansha's Bessatsu Shōnen Magazine between October 9, 2009 and May 9, 2012, compiled in seven volumes.

An OVA anime series was announced by Gonzo in 2005 which would have been directed by Yasufumi Soejima and produced by Geneon, screenplay written by Ubukata himself and character designs by Range Murata (Blue Submarine No.

The film trilogy was animated at GoHands studio and produced by Aniplex, directed by Susumu Kudō and the screenplay was written by Ubukata himself.

[29] Mardock Scramble won the Grand Prize of the 24th Nihon SF Taisho Award by the Science Fiction and Fantasy Writers of Japan (SFWJ) in 2003.