She obtained her GCE Ordinary level certificate from St. Francis Secondary School in Jirapa, in the Upper West Region of Ghana from 1974 to 1979.
[2][3] Amoakohene had her postgraduate education at the University of Ghana where she graduated with a Master of Philosophy degree and a Post-graduate Diploma in Communication Studies.
[2] Since 1992, Ivy Amoakohene has lectured students in various aspects of public relations, qualitative research methods, and mass communication at the University of Ghana.
[5] In 2006, President John Agyekum Kufour appointed Amoakohene to head Ghana's Embassy in Canada as its High Commissioner.
[5][6] In February 2017, President Nana Akuffo-Addo nominated Amoakohene as one of the eleven president-appointed members of the Council of State.